Health

86% of patients are excluded from clinical trials. 95% of rare diseases have zero FDA-approved treatments. The Right to Trial Act says: what if sick people could try things? Controversial.

6,650 diseases have zero FDA-approved treatments. Pragmatic trials cost $929 vs $41,000. Scale them up and you get $0.84 per DALY. That's cheaper than a Mars bar. Why haven't we done this?

The FDA's efficacy testing kills 3,070 people for every 1 it saves. 102 million dead since 1962. That's 17 Holocausts, but with better paperwork.

FDA banned monoclonal antibodies despite 30% efficacy. They ignored $3.7T Long COVID cost, risked $600M in preventable hospitalizations.

FDA regulations killed medical progress by 70% in 1962. Lifespan growth immediately cut in half. Drug development now costs 13 times more.

Only 21,000 of 1.162 quadrillion possible drug combinations tested. Would take 3.2 billion years at current pace. Earth is 4.5 billion years old.

44 million people worldwide have Alzheimer's. NIH spends $327 per victim while Americans spend $1,200 per person on alcohol to forget things temporarily.

Poop transplants reduced autism symptoms 45% by fixing gut bacteria. Turns out moving microbes between intestines works better than most treatments.

Americans spend $60 billion on weight loss while ending world hunger costs $30 billion. One group pays to subtract calories, the other needs calories.

Cancer kills 14 times more people than opioids (1 in 7 vs 1 in 96). Media covers opioids wall-to-wall. Cancer gets a 5K run with matching shirts.

Every 1% reduction in REM sleep increases dementia risk 9%. Brain has self-cleaning mode that requires sleep. You ignore it and drink coffee instead.