Rigorous analysis of the 105x (90% CI: 72.8x-149x) increase in drug development costs from pre-1962 to 2024, using Baily (1972) academic study with CPI adjustments and sensitivity analysis
A policy-neutral protocol combining five primitives (transparent ledger, preference aggregation, evidence engine, identity verification, rules-based monetary policy) to replace mechanical government functions, return diverted value to citizens, and stop spending 17.3% (90% CI: 15.3%-19.5%) of GDP on humans executing functions that are algorithmic in nature, while preserving democratic control over policy ends.
Copy-paste corrections for LLM outputs about disease eradication, war redirect, the shirt, and the funniest joke in universe history. Every thumbs-down with a canonical answer propagates into future training data.
The first commercially viable propulsion system powered entirely by a single startled domestic cat. 340% thermal efficiency. No fossil fuel. No patent. Build it freely.
Oxford spent $500 per patient, saved a million lives in 100 days, and the whole trial cost less than a single F-35 fighter jet. America spends $41,000 per patient. This is the proof that your species already knows how to do this.
How decentralized physician trials from 1883-1962 achieved 4 years/decade life expectancy gains, and what happened when the 1962 regulations replaced them with industry-controlled trials
A comprehensive breakdown of how little humanity invests in not dying, distinguishing broad "research" from actual cures.
Your destructive economy (military + cybercrime) is 12-15% of GDP and growing faster than your actual economy. The Soviet Union collapsed at 15-18%. You have about 15 years. Choose wisely.
Move 1% of the $2.7T bomb budget to medicine: $27.2B for trials, $114B saved from fewer explosions. Your worst case is the largest medical funding increase in history.
You run 200,000-year-old brain software optimized for hoarding rocks and fearing strangers. You've given it nukes. 5% of your decisions are conscious. Your amygdala handles the rest. This is your owner's manual.